This article was originally published on Oct. 9, 2020.
The scientific world is in the midst of a decade-long psychedelic renaissance. This revolution is expanding our understanding of one of the most captivating scientific puzzles: human consciousness. Numerous research fields are revealing new insights into how psychedelics affect the brain and which neural processes underly consciousness.
Multiple studies testing psychedelic drugs for treating mental illness provide compelling evidence of their therapeutic benefit. Treated disorders have included depression, anxiety, post-traumatic stress disorder, anorexia, obsessive compulsive disorder and addiction. Dozens of clinical trials are underway, the majority investigating the therapeutic effect of psilocybin, the active component in so-called magic mushrooms. This natural compound belongs to the class of serotonergic psychedelics — those that activate serotonin (type 2A) receptors.